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What is Dupuytren's Disease?

Dupuytren’s disease, also known as Dupuytren’s contracture or Vikings’ disease, is a prevalent condition typically occurring in middle age or later, with a higher prevalence in men than in women. Although the cause of Dupuytren’s disease remains unknown, it exhibits a higher prevalence in Caucasians and often runs in families. While diabetes, smoking, and high alcohol consumption may co-exist, these associations are not always clear. There are no clearly defined occupational associations. Occasionally, the disease may develop following hand injury or surgery.

The process begins with the formation of firm nodules in the supporting ligaments beneath the skin of the palm. These can extend to form cords which cross the joints. Over a variable amount of time the cords shorten, pulling the finger towards the palm of the hand, known as a contracture. As the disease progresses, the fingers become increasingly bent, and may become fixed in this bent position. The most commonly affected fingers are the ring and little fingers. Less commonly, the disease affects the thumb and index fingers, with the web between these digits narrowing. Disease progression is variable but typically develops slowly over months to years. It tends to be more aggressive in younger patients.

Some individuals with Dupuytren’s disease may also exhibit nodules over the back of the finger knuckles (Garrod’s knuckle pads) and lumps on the soles of the feet. Rarely, men may develop a curvature of the penis.

How is Dupuytrens disease treated?

While there is no cure for Dupuytren’s disease, treatment options aim to address symptoms and improve hand function. Unfortunately, non-surgical options such as injections and splintage are limited in what they can reliably achieve, and surgical intervention is the mainstay of treatment. Surgery does not eliminate the disease entirely, and recurrence may occur over time. The disease may develop in other digits subsequently or even in the other hand.

Surgery is recommended when it becomes difficult to lay the hand flat on a table or when functionality of the hand is affected. The type of surgery and its timing should be discussed with your surgeon.

There are a number of techniques that can be used, depending on the configuration of the disease and the preferences of individual surgeons:

  1. Fasciotomy. The contracted cord of Dupuytren’s disease is simply cut in the palm, in the finger or in both, using a small knife or a needle.
  2. Segmental fasciectomy. Short segments of the cord are removed through one or more small incisions.
  3. Limited fasciectomy. The diseased tissue is removed through a series of connected incisions from the palm and along the finger.
  4. Dermofasciectomy with skin graft. The diseased tissue is removed together with the overlying skin and the skin is replaced with a graft taken usually from the upper arm or groin crease. This procedure is usually undertaken for recurrent disease, severe contractures with a shortage of skin or for extensive disease in a younger individual. and helps prevent recurrence
  5. Fusion of a finger joint. This is a salvage technique which is sometimes recommended in recurrent disease.
  6. Amputation. In rare circumstances and almost always after multiple previous attempts at correction.

Surgery is typically performed under a general anaesthetic or nerve block. The surgery typically takes anywhere between from 1-4 hours depending on the complexity of the operation required, especially when the disease intimately involves important nerves and blood vessels. Almost all patients have the surgery as day cases and go home after a short stay in recovery.

Hand therapy is important in recovering movement and function, especially for more extensive surgery and skin grafts. The recovery is as variable as the surgery, with regard to the degree of improvement achieved and the time to achieve the final position.

What outcomes can I expect from surgery?

The outcome of the surgery is not always predictable and is dependent on many factors. These include disease severity and the complexity of surgery thus required, if the disease is recurrent, and the post operative course including complications, and compliance with hand therapy. The latter is critical in avoiding long term stiffness from surgery.

Dupuytrens surgery is generally safe. However, like all surgery, there are potential risks of complication. Generic risks include pain, bleeding, infection, or wound healing problems (higher chance if skin grafts are needed). The nerves and arteries that supply the finger can be injured. Technical factors may mean that the contracture cannot be fully released or the disease fully removed. Finally, surgery cannot influence genetics, and so there is always a risk that the Dupuytrens returns, either in the same position or elsewhere.

What questions should I ask my plastic surgeon about Dupuytren's disease surgery?

  • Are you vocationally registered with the Medical Council of New Zealand as a specialist plastic surgeon?

  • Are you a member of the New Zealand Association of Plastic Surgeons?

  • Will the procedure be conducted in a hospital or office-based setting, and is the facility accredited for this type of surgery?

  • What type of anaesthesia is needed for this procedure?

  • Based on my medical history and condition, is surgery the best option for me? If so, am I a suitable candidate for this surgery?

  • Which surgical technique do you recommend for my case, and why?

  • What are the realistic expectations for the outcome of this procedure in my case?

  • What steps or lifestyle changes are necessary for me to get the best result from my surgery?

  • What is the anticipated duration of recovery, and what assistance will I need during this period?

  • What potential risks and complications are associated with this procedure? How would you manage these should they arise?

  • How will my results change over time?

  • If I’m unhappy with the outcome, what recourse options are available?